METUPUK at the UK Interdisciplinary Breast Cancer Symposium

METUPUK (Metastatic Exchange To Unleash Power) attended the 2024 United Kingdom’s Interdisciplinary Breast Cancer Symposium in Birmingham, hosted by Breast Cancer Now and supported by numerous partners. It was a

NICE invites comments from the public on the draft guidance to not recommend the parp inhibitor talazoparib

METUPUK are disappointed by the National Institute of Clinical Excellence (NICE) decision to not recommend talazoparib (Talzenna ®, Pfizer Ltd.) for treating HER2-negative, locally advanced or metastatic breast cancer with

On the trail of a Clinical Trial…

On the trail of a Clinical Trial…

METUPUK historically maintained their own in-house clinical trial database for metastatic trials in the UK as there was no one source that contained them all. It used the key sites used across the UK; Cancer Research UK, Be Part of Research, ISRCTN and

Leaping forward to 2022, surely by now one of them must be THE accurate, easily searchable source of breast cancer trials? If not, how do our oncologists quickly and accurately find the best trials for their metastatic patients?

And where do patients start when looking for a metastatic trial themselves?

METUPUK are delighted by the Scottish Medicines Consortium (SMC) acceptance of Enhertu (trastuzumab deruxtecan) for routine use on the NHS.

METUPUK are delighted by the Scottish Medicines Consortium (SMC) acceptance of Enhertu (trastuzumab deruxtecan) for routine use on the NHS. The Scottish Medicines Consortium (SMC) has accepted: Trastuzumab deruxtecan (Enhertu)

Philippa Hetherington Remembered

We had to confirm back on the 5th November the heartbreaking news that the wonderful Philippa Hetherington had died 💔

She was an absolute force of intellectual nature for breast cancer in general, not just Inflammatory Breast Cancer.

Did you know that the Trodelvy campaign in England for TNBC was HER campaign?

Trodelvy Now! Latest Update

Trodelvy Approved by NICE

METUPUK are delighted that NICE has accepted Trodelvy (sacituzumab govitecan) for routine use on the NHS in England for the treatment of patients with unresectable locally advanced or metastatic triple-negative breast cancer who have received two or more prior lines of systemic therapies. This follows on from the decision to approve Trodelvy in NHS Scotland in March 2022. Wales and Northern Ireland normally follow decisions by NHS England and we hope that Trodelvy will be made available to every patient who is eligible without delay.

Why we need MBC research more than ever

Why we need MBC research more than ever

At METUPUK, we dream of the day when metastatic breast cancer (MBC) is downgraded from an incurable to a chronic illness. The only way this will be possible is through new scientific research. We urgently need more research into this deadly disease.
We need more clinical research into MBC, including clinical trials. These are crucial for determining which are the most effective treatment options and for bringing new drug treatments to patients.



Of all the subtypes of metastatic breast cancer, metastatic Triple Negative Breast Cancer (TNBC) is the hardest to treat with the worst prognosis. While new advances in the treatment of hormone positive MBC and Her2 MBC have helped some patients live for a number of years, average life expectancy for someone with metastatic TNBC is just 12-18 months.